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BDBM50132538 2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole-4-carboxylic acid (1-aza-bicyclo[2.2.2]oct-3-yl)-amide::CHEMBL110549

SMILES: CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1

InChI Key: InChIKey=BCVLPDNMZNZKHT-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132538   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50132538
PNG
(2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Show SMILES CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1
Show InChI InChI=1S/C29H38N6O2/c1-2-18-37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)20-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-19-33-12-10-21(24)11-13-33/h3-9,21,24H,2,10-20H2,1H3,(H,30,32)(H,31,36)
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes


Bioorg Med Chem Lett 13: 3177-80 (2003)


Article DOI: 10.1016/s0960-894x(03)00706-6
BindingDB Entry DOI: 10.7270/Q2GH9HCP
More data for this
Ligand-Target Pair
Serotonin (5-HT) receptor


(Rattus norvegicus (rat))
BDBM50132538
PNG
(2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Show SMILES CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1
Show InChI InChI=1S/C29H38N6O2/c1-2-18-37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)20-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-19-33-12-10-21(24)11-13-33/h3-9,21,24H,2,10-20H2,1H3,(H,30,32)(H,31,36)
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
56n/an/an/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat cerebral cortex membranes


Bioorg Med Chem Lett 13: 3177-80 (2003)


Article DOI: 10.1016/s0960-894x(03)00706-6
BindingDB Entry DOI: 10.7270/Q2GH9HCP
More data for this
Ligand-Target Pair