BDBM50132538 2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole-4-carboxylic acid (1-aza-bicyclo[2.2.2]oct-3-yl)-amide::CHEMBL110549

SMILES: CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1

InChI Key: InChIKey=BCVLPDNMZNZKHT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132538   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50132538 (2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...) Show SMILES CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 Show InChI InChI=1S/C29H38N6O2/c1-2-18-37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)20-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-19-33-12-10-21(24)11-13-33/h3-9,21,24H,2,10-20H2,1H3,(H,30,32)(H,31,36)	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) Article DOI: 10.1016/s0960-894x(03)00706-6 BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50132538 (2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...) Show SMILES CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 Show InChI InChI=1S/C29H38N6O2/c1-2-18-37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)20-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-19-33-12-10-21(24)11-13-33/h3-9,21,24H,2,10-20H2,1H3,(H,30,32)(H,31,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) Article DOI: 10.1016/s0960-894x(03)00706-6 BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair