BDBM50132881 2-{2-Carbamoyl-6-[(4-{[2-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyloxy)-acetylamino]-methyl}-phenylamino)-methyl]-3-methyl-phenoxy}-3-hydroxy-5-methoxy-4-methyl-benzoic acid::CHEMBL111721

SMILES COc1cc(C(O)=O)c(Oc2c(CNc3ccc(CNC(=O)CO[C@@H]4C[C@H](C)CC[C@H]4C(C)C)cc3)ccc(C)c2C(N)=O)c(O)c1C

InChI Key InChIKey=PHPRQHYNDILUAH-YHGBQTNRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132881   

TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50132881(2-{2-Carbamoyl-6-[(4-{[2-((1R,2S,5R)-2-isopropyl-5...)
Affinity DataIC50:  600nMAssay Description:Plasminogen Activator Inhibitor-1 (PAI-1) activity was determined by inhibition of Urokinase-type plasminogen activator using primary assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed