BDBM50133003 4-(3-(piperidin-1-yl)propoxy)benzonitrile::4-(3-Piperidin-1-yl-propoxy)-benzonitrile::CHEMBL129257::UCL-2138

SMILES N#Cc1ccc(OCCCN2CCCCC2)cc1

InChI Key InChIKey=RHMNKKOAWUCDRK-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133003   

TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50133003(UCL-2138 | CHEMBL129257 | 4-(3-Piperidin-1-yl-prop...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in HEL293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50133003(UCL-2138 | CHEMBL129257 | 4-(3-Piperidin-1-yl-prop...)
Affinity DataKi:  25nMAssay Description:Binding affinity to the human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50133003(UCL-2138 | CHEMBL129257 | 4-(3-Piperidin-1-yl-prop...)
Affinity DataKi:  25.1nMAssay Description:Mean binding affinity for human H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133003(UCL-2138 | CHEMBL129257 | 4-(3-Piperidin-1-yl-prop...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to the human histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50133003(UCL-2138 | CHEMBL129257 | 4-(3-Piperidin-1-yl-prop...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed