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BDBM50133108 8,9-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid ethyl ester::CHEMBL128824

SMILES: CCOC(=O)c1nc2n(n1)c1c(Cl)c(Cl)ccc1[nH]c2=O

InChI Key: InChIKey=KEJJWXVOYZCLJF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133108   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ionotropic glutamate receptor NMDA 1/2D


(RAT)
BDBM50133108
PNG
(8,9-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...)
Show SMILES CCOC(=O)c1nc2n(n1)c1c(Cl)c(Cl)ccc1[nH]c2=O
Show InChI InChI=1S/C12H8Cl2N4O3/c1-2-21-12(20)9-16-10-11(19)15-6-4-3-5(13)7(14)8(6)18(10)17-9/h3-4H,2H2,1H3,(H,15,19)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
4.80E+3n/an/an/an/an/an/an/an/a



Moscow State University

Curated by ChEMBL


Assay Description
Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDA


J Med Chem 46: 4063-9 (2003)


Article DOI: 10.1021/jm030833a
BindingDB Entry DOI: 10.7270/Q2445KVC
More data for this
Ligand-Target Pair