BDBM50133233 1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine::CHEMBL131736

SMILES CC(N)Cc1cn(C)c2ccc3OCCCc3c12

InChI Key InChIKey=HPEOSNKVEAJRAK-UHFFFAOYSA-N

Data  4 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50133233   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataKi:  0.200nMAssay Description:In vitro inhibitory constant against [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataKi:  2.70nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2C receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataKi:  11nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2B receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataKi:  28nMAssay Description:Inhibitory constant against cloned human 5-hydroxytryptamine 2A receptor using with [125I]- DOI radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataEC50: >1.00E+4nMAssay Description:Tested for functional response on CHO cells expressing cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibition of [125I]DOI binding to 5-hydroxytryptamine 2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataIC50:  1.22E+4nMAssay Description:In vitro inhibitory concentration required against [3H]8-OH-DPAT binding to cloned human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50133233(1-Methyl-2-(3-methyl-3,7,8,9-tetrahydro-pyrano[3,2...)
Affinity DataEC50:  134nMAssay Description:In vitro relative agonist activity against 5-hydroxytryptamine 2A using PI assay in rat vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed