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BDBM50133289 CHEMBL3634953

SMILES: OC(=O)c1ccc(O)c2nc(ccc12)C(=O)N1CCOCC1

InChI Key: InChIKey=JGHYGVUEJGFURT-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133289   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))
BDBM50133289
PNG
(CHEMBL3634953)
Show SMILES OC(=O)c1ccc(O)c2nc(ccc12)C(=O)N1CCOCC1
Show InChI InChI=1S/C15H14N2O5/c18-12-4-2-10(15(20)21)9-1-3-11(16-13(9)12)14(19)17-5-7-22-8-6-17/h1-4,18H,5-8H2,(H,20,21)
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Similars

Article
PubMed
n/an/a 5.10E+3n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human JMJD2A using biotinylated histone H3 as substrate by AlphaScreen assay


Eur J Med Chem 105: 145-55 (2015)


Article DOI: 10.1016/j.ejmech.2015.09.013
BindingDB Entry DOI: 10.7270/Q2ZG6V2N
More data for this
Ligand-Target Pair