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BDBM50133570 CHEMBL116326::N-[2-(2,6-Dichloro-benzyl)-thiazol-4-yl]-2-(N'-methyl-hydrazino)-acetamide

SMILES: CNNCC(=O)Nc1csc(Cc2c(Cl)cccc2Cl)n1

InChI Key: InChIKey=XGLUBSMTWTWWJR-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133570   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-Dependent Kinase 5 (CDK5)


(Homo sapiens (Human))
BDBM50133570
PNG
(CHEMBL116326 | N-[2-(2,6-Dichloro-benzyl)-thiazol-...)
Show SMILES CNNCC(=O)Nc1csc(Cc2c(Cl)cccc2Cl)n1
Show InChI InChI=1S/C13H14Cl2N4OS/c1-16-17-6-12(20)18-11-7-21-13(19-11)5-8-9(14)3-2-4-10(8)15/h2-4,7,16-17H,5-6H2,1H3,(H,18,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Pharmacia Corporation

Curated by ChEMBL


Assay Description
Ability to inhibit Cyclin-dependent kinase 5-p35.


Bioorg Med Chem Lett 13: 3491-5 (2003)


Article DOI: 10.1016/s0960-894x(03)00726-1
BindingDB Entry DOI: 10.7270/Q2XG9QHN
More data for this
Ligand-Target Pair