BDBM50134248 Alpha-Hydroxy-Midazolam::CHEMBL1188::US9333197, Hydroxymidazolam::[8-Chloro-6-(2-fluoro-phenyl)-4H-2,5,10b-triaza-benzo[e]azulen-1-yl]-methanol

SMILES OCc1ncc2CN=C(c3ccccc3F)c3cc(Cl)ccc3-n12

InChI Key InChIKey=QHSMEGADRFZVNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134248   

TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50134248(Alpha-Hydroxy-Midazolam | CHEMBL1188 | US9333197, ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity for Cytochrome P450 3A4; Range = 1-10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM50134248(Alpha-Hydroxy-Midazolam | CHEMBL1188 | US9333197, ...)
Affinity DataIC50:  2.70E+3nMAssay Description:Six test compound concentrations (0.1, 0.25, 1, 2.5, 10, 25 μM in DMSO; final DMSO concentration=0.26%) are incubated with human liver microsome...More data for this Ligand-Target Pair
In DepthDetails US Patent