BDBM50134328 CHEMBL124349::Phenyl-acetic acid (1R,3R,5S)-8-(4-chloro-benzenesulfonylaminocarbonyl)-8-aza-bicyclo[3.2.1]oct-3-yl ester::Phenyl-acetic acid (1S,3R,5R)-8-(4-chloro-benzenesulfonylaminocarbonyl)-8-aza-bicyclo[3.2.1]oct-3-yl ester

SMILES Clc1ccc(cc1)S(=O)(=O)NC(=O)N1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)Cc1ccccc1

InChI Key InChIKey=MYFOQMDKPWDPGC-BWTSREIZSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50134328   

TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50134328(CHEMBL124349 | Phenyl-acetic acid (1R,3R,5S)-8-(4-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory constant against human steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50134328(CHEMBL124349 | Phenyl-acetic acid (1R,3R,5S)-8-(4-...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibitory activity against Steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50134328(CHEMBL124349 | Phenyl-acetic acid (1R,3R,5S)-8-(4-...)
Affinity DataIC50:  6.27E+3nMAssay Description:Inhibitory concentration against human steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50134328(CHEMBL124349 | Phenyl-acetic acid (1R,3R,5S)-8-(4-...)
Affinity DataIC50:  910nMAssay Description:Inhibitory concentration against human steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50134328(CHEMBL124349 | Phenyl-acetic acid (1R,3R,5S)-8-(4-...)
Affinity DataIC50:  6.72E+3nMAssay Description:Inhibitory activity against Steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed