BDBM50134333 CHEMBL331089::Phenyl-acetic acid (1R,3R,5S)-8-(3,5-bis-trifluoromethyl-benzenesulfonylaminocarbonyl)-8-aza-bicyclo[3.2.1]oct-3-yl ester::Phenyl-acetic acid (1S,3R,5R)-8-(3,5-bis-trifluoromethyl-benzenesulfonylaminocarbonyl)-8-aza-bicyclo[3.2.1]oct-3-yl ester

SMILES FC(F)(F)c1cc(cc(c1)S(=O)(=O)NC(=O)N1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)Cc1ccccc1)C(F)(F)F

InChI Key InChIKey=PPEKRJZEOBNGOP-BWTSREIZSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50134333   

TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(CHEMBL331089 | Phenyl-acetic acid (1R,3R,5S)-8-(3,...)
Affinity DataKi:  76nMAssay Description:Inhibitory activity against Steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(CHEMBL331089 | Phenyl-acetic acid (1R,3R,5S)-8-(3,...)
Affinity DataKi:  76nMAssay Description:Inhibitory constant against human steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(CHEMBL331089 | Phenyl-acetic acid (1R,3R,5S)-8-(3,...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibitory concentration against human steroid sulfatase expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(CHEMBL331089 | Phenyl-acetic acid (1R,3R,5S)-8-(3,...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibitory constant against purified human Steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(CHEMBL331089 | Phenyl-acetic acid (1R,3R,5S)-8-(3,...)
Affinity DataIC50:  84nMAssay Description:Inhibitory activity against purified human Steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Novartis Research Institute Vienna

Curated by ChEMBL
LigandPNGBDBM50134333(CHEMBL331089 | Phenyl-acetic acid (1R,3R,5S)-8-(3,...)
Affinity DataIC50:  84nMAssay Description:Inhibitory concentration against human steroid sulfataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed