BDBM50134431 CHEMBL3747181
SMILES CC(C)c1c(nn2c(Nc3cc(Cl)cc(Cl)c3)c(cnc12)C(N)=O)S(C)(=O)=O
InChI Key InChIKey=WGGRXSZLNZHDJO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50134431
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Sanofi Research Center
Curated by ChEMBL
Sanofi Research Center
Curated by ChEMBL
Affinity DataIC50: 507nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Sanofi Research Center
Curated by ChEMBL
Sanofi Research Center
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair