BDBM50134526 2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-cyclopropanecarboxylic acid::CHEMBL125588

SMILES OC(=O)C1CC1c1ccccc1-c1csc(c1)-c1ccccc1OCc1ccccc1

InChI Key InChIKey=DCYHRPUPJCRAGG-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50134526   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  3nMAssay Description:Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  120nMAssay Description:Ability to inhibit the binding of human DP receptor to PGD-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  300nMAssay Description:Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  400nMAssay Description:Ability to inhibit the binding of human Thromboxane A2 receptor to TXA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  710nMAssay Description:Ability to inhibit the binding of human IP receptor to Prostaglandin I2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  2.30E+3nMAssay Description:Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  2.20E+4nMAssay Description:Ability to inhibit the binding of human FP receptor to PGD-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
Affinity DataKi:  4.80E+4nMAssay Description:Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed