BDBM50134587 CHEMBL3746157

SMILES NC(=O)c1nc(-c2ccns2)c2ccccn12

InChI Key InChIKey=YTNDIPNEFMPJKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134587   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50134587(CHEMBL3746157)
Affinity DataIC50:  370nMAssay Description:Inhibition of p38alpha phosphorylation in human TNFalpha-stimulated U937 cells treated 1 hr before by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 3(Homo sapiens (Human))
Takeda California

Curated by ChEMBL
LigandPNGBDBM50134587(CHEMBL3746157)
Affinity DataIC50:  4nMAssay Description:Inhibition of MKK3 (unknown origin) using [gamma-33P]-ATP after 20 mins by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed