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BDBM50134599 CHEMBL3747486

SMILES: Cn1c2nc(NC3CCCCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O

InChI Key: InChIKey=IRALUAJNHAVHJX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134599   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
c-Jun N-terminal kinase, JNK


(Homo sapiens (Human))
BDBM50134599
PNG
(CHEMBL3747486)
Show SMILES Cn1c2nc(NC3CCCCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O
Show InChI InChI=1S/C20H20F2N4O2/c1-26-18-12(11-23-20(25-18)24-14-5-3-2-4-6-14)9-17(19(26)27)28-16-8-7-13(21)10-15(16)22/h7-11,14H,2-6H2,1H3,(H,23,24,25)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.61E+4n/an/an/an/an/an/a



Semmelweis University

Curated by ChEMBL


Assay Description
Inhibition of JNK1 (unknown origin)


Bioorg Med Chem Lett 26: 424-8 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.099
BindingDB Entry DOI: 10.7270/Q24T6M6J
More data for this
Ligand-Target Pair