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BDBM50134725 CHEMBL3746877

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1cc(ccc1-[#8])-[#6]-1-[#8]-c2cc(-[#8])c(-[#6])c(-[#8])c2-[#6](=O)-[#6]-1=O

InChI Key: InChIKey=BQHNWTLZOFCOPV-OVCLIPMQNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134725   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50134725
PNG
(CHEMBL3746877)
Show SMILES CC(C)=CCC\C(C)=C\Cc1cc(ccc1O)C1Oc2cc(O)c(C)c(O)c2C(=O)C1=O
Show InChI InChI=1/C26H28O6/c1-14(2)6-5-7-15(3)8-9-17-12-18(10-11-19(17)27)26-25(31)24(30)22-21(32-26)13-20(28)16(4)23(22)29/h6,8,10-13,26-29H,5,7,9H2,1-4H3/b15-8+
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Gyeongsang National University

Curated by ChEMBL


Assay Description
Inhibition of monophenolase activity of mushroom tyrosinase using L-tyrosine as substrate preincubated with substrate for 10 mins followed by protein...


Bioorg Med Chem 24: 153-9 (2016)


Article DOI: 10.1016/j.bmc.2015.11.040
BindingDB Entry DOI: 10.7270/Q2RN39PT
More data for this
Ligand-Target Pair
Tyrosinase


(Agaricus bisporus (Common mushroom))
BDBM50134725
PNG
(CHEMBL3746877)
Show SMILES CC(C)=CCC\C(C)=C\Cc1cc(ccc1O)C1Oc2cc(O)c(C)c(O)c2C(=O)C1=O
Show InChI InChI=1/C26H28O6/c1-14(2)6-5-7-15(3)8-9-17-12-18(10-11-19(17)27)26-25(31)24(30)22-21(32-26)13-20(28)16(4)23(22)29/h6,8,10-13,26-29H,5,7,9H2,1-4H3/b15-8+
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Gyeongsang National University

Curated by ChEMBL


Assay Description
Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated with substrate for 10 mins followed by protein addit...


Bioorg Med Chem 24: 153-9 (2016)


Article DOI: 10.1016/j.bmc.2015.11.040
BindingDB Entry DOI: 10.7270/Q2RN39PT
More data for this
Ligand-Target Pair