BDBM50134803 5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone::CHEMBL144205

SMILES C[C@@H]1NC(=O)[C@H](CCCCCC(=O)C2CO2)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC1=O

InChI Key InChIKey=WJKBTCSWQYZOOK-NNZQMTATSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134803   

TargetHistone deacetylase 4(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Histone deacetylase 4 in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataEC50:  3.60E+5nMAssay Description:Tested for inhibition of Histone deacetylase 6 induced acetylated tubulin in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134803(5,8-Dimethyl-11-(6-oxiranyl-6-oxo-hexyl)-decahydro...)
Affinity DataEC50:  110nMAssay Description:Inhibition of Histone deacetylase 1 induced acetylated histone in mammalian cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed