BDBM50134917 CHEMBL3747766

SMILES CC(C)(C)OC(=O)N1C[C@H](Nc2nc3cc(F)ccc3[nH]2)[C@H](C1)OCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ISSOLUDHEZMZKW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50134917   

TargetBeta-secretase 1(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134917(CHEMBL3747766)
Affinity DataIC50: 120nMAssay Description:Inhibition of BACE1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134917(CHEMBL3747766)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BACE1 in human PC12 cells expressing APP Sweden mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134917(CHEMBL3747766)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetCathepsin D(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134917(CHEMBL3747766)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed