BDBM50134931 5-(7-Chloro-quinolin-4-ylamino)-2-diethylaminomethyl-phenol::5-(7-chloroquinolin-4-ylamino)-2-((diethylamino)methyl)phenol::CHEMBL147587::isoquine

SMILES: CCN(CC)Cc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1O

InChI Key: InChIKey=QGFYFOHMBDMGBZ-UHFFFAOYSA-N

Data: 13 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50134931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C8 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50134931 (isoquine | 5-(7-chloroquinolin-4-ylamino)-2-((diet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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