BDBM50135292 1-(2-Chloro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL338612

SMILES Fc1ccc(Sc2ccc3N(C(=O)NCc3n2)c2ccccc2Cl)cc1

InChI Key InChIKey=WJKXYGGZKSIWQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135292   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135292(1-(2-Chloro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,...)
Affinity DataIC50:  69nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135292(1-(2-Chloro-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,...)
Affinity DataIC50:  530nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed