BDBM50135527 (-)-cis-rotenone::(-)-rotenone::(2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one::5'beta-rotenone::Barbasco::CHEMBL429023::Canex::Noxfire::[2R-(2alpha,6aalpha,12aalpha)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3-H][1]benzopyran-6(6aH)-one::rotenone

SMILES: CC(=C)[C@H]1Cc2c(ccc3c2O[C@@H]4COc5cc(c(cc5[C@@H]4C3=O)OC)OC)O1

InChI Key: InChIKey=JUVIOZPCNVVQFO-UHFFFAOYSA-N

Data: 11 IC50

PDB links: 13 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50135527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 2 (Human)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
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NADH-ubiquinone oxidoreductase chain 1 (Bovine)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
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Acyl carrier protein,/NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Bovine)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
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NADH-ubiquinone oxidoreductase chain 4 (Human)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (quinone), mitochondrial (malaria parasite P. falciparum)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Baker's yeast)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Pancreatic triacylglycerol lipase (Pig)	BDBM50135527 (rotenone | (-)-cis-rotenone | (-)-rotenone | 5'bet...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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