BDBM50135835 (isoquinolin-1-ylamino)methylenediphosphonic acid::1-[(Bis-phosphono-methyl)-amino]-isoquinolinium::CHEMBL291727::[(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHONIC ACID

SMILES: c1ccc2c(c1)ccnc2NC(P(=O)(O)O)P(=O)(O)O

InChI Key: InChIKey=JPVMIOWESIQIGB-UHFFFAOYSA-N

Data: 2 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135835   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Farnesyl pyrophosphate synthase (Human)	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
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Polyprenyl synthetase family protein (Leishmania donovani)	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
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1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli (strain K12))	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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1-deoxy-D-xylulose 5-phosphate reductoisomerase (Escherichia coli (strain K12))	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Farnesyl pyrophosphate synthase (Human)	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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1-deoxy-D-xylulose 5-phosphate reductoisomerase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM50135835 ([(ISOQUINOLIN-1-YLAMINO)-PHOSPHONO-METHYL]-PHOSPHO...) Show SMILES Show InChI	GoogleScholar	UniChem		3.27E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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