BDBM50135934 3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-propionic acid::CHEMBL68399

SMILES CC(C)CCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O

InChI Key InChIKey=FUZLEHIZFGSVSF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135934   

TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50:  5nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50:  2.70nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase M(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase M(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed