BDBM50135945 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::2-(2-Aminomethyl-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid (3-fluoro-2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL151939

SMILES: NCc1ccccc1-n1nc(cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)C(F)(F)F

InChI Key: InChIKey=TYPXEIGMGZWOGB-UHFFFAOYSA-N

Data: 14 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50135945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasma kallikrein (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vitamin K-dependent protein C (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Chymotrypsinogen A (Bovine)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor IX (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Urokinase-type plasminogen activator (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor VII (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tissue-type plasminogen activator (Human)	BDBM50135945 (1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoyl...) Show SMILES Show InChI	GoogleScholar	UniChem		>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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