BDBM50136047 2-(4-Butoxy-phenyl)-pyrazine::CHEMBL150146

SMILES CCCCOc1ccc(cc1)-c1cnccn1

InChI Key InChIKey=CWDVFUCLYPBQNG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50136047   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136047(2-(4-Butoxy-phenyl)-pyrazine | CHEMBL150146)
Affinity DataIC50:  3.68E+4nMAssay Description:Concentration required to inhibit cytochrome P450 2C9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136047(2-(4-Butoxy-phenyl)-pyrazine | CHEMBL150146)
Affinity DataIC50:  6.59E+3nMAssay Description:Concentration required to inhibit cytochrome P450 2D6.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136047(2-(4-Butoxy-phenyl)-pyrazine | CHEMBL150146)
Affinity DataIC50:  7.86E+3nMAssay Description:Concentration required to inhibit cytochrome P450 19A1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136047(2-(4-Butoxy-phenyl)-pyrazine | CHEMBL150146)
Affinity DataIC50: >46nMAssay Description:Concentration required to inhibit cytochrome P450 1A2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50136047(2-(4-Butoxy-phenyl)-pyrazine | CHEMBL150146)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to inhibit cytochrome P450 3A4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed