BDBM50136185 4-[1-(4-Fluoro-phenyl)-2-piperidin-4-yl-ethoxy]-benzonitrile::CHEMBL150562

SMILES Fc1ccc(cc1)C(CC1CCNCC1)Oc1ccc(cc1)C#N

InChI Key InChIKey=VWROIWGESBEGLL-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136185   

TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136185(4-[1-(4-Fluoro-phenyl)-2-piperidin-4-yl-ethoxy]-be...)
Affinity DataKi:  16.9nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136185(4-[1-(4-Fluoro-phenyl)-2-piperidin-4-yl-ethoxy]-be...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136185(4-[1-(4-Fluoro-phenyl)-2-piperidin-4-yl-ethoxy]-be...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed