BDBM50136188 2-[3-Phenyl-3-(2-trifluoromethyl-phenoxy)-propyl]-1,2,3,4-tetrahydro-isoquinoline-6,7-diol::CHEMBL346619

SMILES Oc1cc2CCN(CCC(Oc3ccccc3C(F)(F)F)c3ccccc3)Cc2cc1O

InChI Key InChIKey=KCMGKHORSUDFCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136188   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136188(2-[3-Phenyl-3-(2-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against serotonin transporter (SERT) by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136188(2-[3-Phenyl-3-(2-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Faes Farma

Curated by ChEMBL
LigandPNGBDBM50136188(2-[3-Phenyl-3-(2-trifluoromethyl-phenoxy)-propyl]-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed