BDBM50136265 (2S,3S)-1-Ethyl-piperidine-2,3-dicarboxylic acid 3-hydroxyamide 2-{[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-amide}::CHEMBL337849

SMILES CCN1CCC[C@@H]([C@H]1C(=O)Nc1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key InChIKey=ODDGTPKMNMBICU-UPVQGACJSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50136265   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136265((2S,3S)-1-Ethyl-piperidine-2,3-dicarboxylic acid 3...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136265((2S,3S)-1-Ethyl-piperidine-2,3-dicarboxylic acid 3...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136265((2S,3S)-1-Ethyl-piperidine-2,3-dicarboxylic acid 3...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibitory activity of the compound against matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136265((2S,3S)-1-Ethyl-piperidine-2,3-dicarboxylic acid 3...)
Affinity DataIC50:  8nMAssay Description:In vitro binding affinity against porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed