BDBM50136480 CHEMBL3038081::Cyclosporin A analogue

SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](SCCN(C)C)N(C)C1=O)C(C)C

InChI Key InChIKey=KXFVFUYEOVDVGN-WHOUCOBPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136480   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Centre De Recherche De Paris

Curated by ChEMBL
LigandPNGBDBM50136480(CHEMBL3038081 | Cyclosporin A analogue)
Affinity DataIC50:  47nMAssay Description:Immunosuppressive activity was measured by inhibition of the IL-2 production in Jurkat cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Centre De Recherche De Paris

Curated by ChEMBL
LigandPNGBDBM50136480(CHEMBL3038081 | Cyclosporin A analogue)
Affinity DataIC50:  47nMAssay Description:In vitro inhibitory activity against HIV-1 RT in CEM4 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed