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BDBM50136628 CHEMBL3752895

SMILES: Cc1cc(cc(C)c1F)S(=O)(=O)N1C[C@H](F)C[C@@H]1c1ccc(F)cc1

InChI Key: InChIKey=IWSOJDYXNTZUGK-NVXWUHKLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136628   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily A member 1


(Homo sapiens (Human))
BDBM50136628
PNG
(CHEMBL3752895)
Show SMILES Cc1cc(cc(C)c1F)S(=O)(=O)N1C[C@H](F)C[C@@H]1c1ccc(F)cc1
Show InChI InChI=1S/C18H18F3NO2S/c1-11-7-16(8-12(2)18(11)21)25(23,24)22-10-15(20)9-17(22)13-3-5-14(19)6-4-13/h3-8,15,17H,9-10H2,1-2H3/t15-,17-/m1/s1
PDB

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Similars

Article
PubMed
n/an/a 380n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human TRPA1


Bioorg Med Chem Lett 26: 495-8 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.088
BindingDB Entry DOI: 10.7270/Q23R0VRB
More data for this
Ligand-Target Pair