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BDBM50136927 4-Chloro-N-[3-chloro-7-(cyclopropylmethyl-amino)-1H-indazol-5-yl]-benzenesulfonamide::CHEMBL154601

SMILES: Clc1n[nH]c2c(NCC3CC3)cc(NS(=O)(=O)c3ccc(Cl)cc3)cc12

InChI Key: InChIKey=WZSUZPBMPKWIPS-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methylthioadenosine Nucleosidase(MTAN)


(Escherichia coli (strain K12))
BDBM50136927
PNG
(4-Chloro-N-[3-chloro-7-(cyclopropylmethyl-amino)-1...)
Show SMILES Clc1n[nH]c2c(NCC3CC3)cc(NS(=O)(=O)c3ccc(Cl)cc3)cc12
Show InChI InChI=1S/C17H16Cl2N4O2S/c18-11-3-5-13(6-4-11)26(24,25)23-12-7-14-16(21-22-17(14)19)15(8-12)20-9-10-1-2-10/h3-8,10,20,23H,1-2,9H2,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
500n/an/an/an/an/an/an/an/a



Quorex Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)


J Med Chem 46: 5663-73 (2003)


Article DOI: 10.1021/jm0302039
BindingDB Entry DOI: 10.7270/Q279443D
More data for this
Ligand-Target Pair