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BDBM50137192 2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzylamino}-ethoxy)-ethanol::CHEMBL421326

SMILES: OCCOCCNCc1ccc(cc1)-c1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1

InChI Key: InChIKey=FTHVRWNSFRDQNV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137192   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1


(Homo sapiens (Human))
BDBM50137192
PNG
(2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyrid...)
Show SMILES OCCOCCNCc1ccc(cc1)-c1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1
Show InChI InChI=1S/C26H26N4O2S/c31-12-14-32-13-11-27-17-18-1-3-19(4-2-18)25-16-24-26(33-25)23(8-10-29-24)30-21-5-6-22-20(15-21)7-9-28-22/h1-10,15-16,27-28,31H,11-14,17H2,(H,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against Vascular endothelial growth factor receptor


Bioorg Med Chem Lett 14: 21-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.030
BindingDB Entry DOI: 10.7270/Q2FT8KFT
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50137192
PNG
(2-(2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyrid...)
Show SMILES OCCOCCNCc1ccc(cc1)-c1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1
Show InChI InChI=1S/C26H26N4O2S/c31-12-14-32-13-11-27-17-18-1-3-19(4-2-18)25-16-24-26(33-25)23(8-10-29-24)30-21-5-6-22-20(15-21)7-9-28-22/h1-10,15-16,27-28,31H,11-14,17H2,(H,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against epidermal growth factor receptor


Bioorg Med Chem Lett 14: 21-4 (2003)


Article DOI: 10.1016/j.bmcl.2003.10.030
BindingDB Entry DOI: 10.7270/Q2FT8KFT
More data for this
Ligand-Target Pair