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BDBM50137537 CHEMBL369391::N-[3-(2-Dimethylamino-ethyl)-2-methyl-furo[3,2-b]pyridin-5-yl]-4-fluoro-benzamide

SMILES: CN(C)CCc1c(C)oc2ccc(NC(=O)c3ccc(F)cc3)nc12

InChI Key: InChIKey=GQSPCQAPLIPSQV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137537   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM50137537
PNG
(CHEMBL369391 | N-[3-(2-Dimethylamino-ethyl)-2-meth...)
Show SMILES CN(C)CCc1c(C)oc2ccc(NC(=O)c3ccc(F)cc3)nc12
Show InChI InChI=1S/C19H20FN3O2/c1-12-15(10-11-23(2)3)18-16(25-12)8-9-17(21-18)22-19(24)13-4-6-14(20)7-5-13/h4-9H,10-11H2,1-3H3,(H,21,22,24)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
14n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound for human 5-hydroxytryptamine 1F receptor


Bioorg Med Chem Lett 14: 167-70 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.091
BindingDB Entry DOI: 10.7270/Q2S46RCF
More data for this
Ligand-Target Pair