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BDBM50138206 (S)-3-(4-Dimethylamino-phenyl)-5-phenethyl-1-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2-thioxo-imidazolidin-4-one::CHEMBL108025

SMILES: CN(C)c1ccc(cc1)-n1c(O)c(CCc2ccccc2)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=S

InChI Key: InChIKey=QTMYWSOFBMYDIL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138206   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))
BDBM50138206
PNG
((S)-3-(4-Dimethylamino-phenyl)-5-phenethyl-1-[2'-(...)
Show SMILES CN(C)c1ccc(cc1)-n1c(O)c(CCc2ccccc2)n(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c1=S
Show InChI InChI=1S/C33H31N7OS/c1-38(2)26-17-19-27(20-18-26)40-32(41)30(21-14-23-8-4-3-5-9-23)39(33(40)42)22-24-12-15-25(16-13-24)28-10-6-7-11-29(28)31-34-36-37-35-31/h3-13,15-20,41H,14,21-22H2,1-2H3,(H,34,35,36,37)
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UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of ghrelin binding to Growth hormone secretagogue receptor expressed in BHK cells


Bioorg Med Chem Lett 14: 317-20 (2003)


Article DOI: 10.1016/j.bmcl.2003.11.012
BindingDB Entry DOI: 10.7270/Q2SX6CND
More data for this
Ligand-Target Pair