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BDBM50138223 CHEMBL3753526

SMILES: C[C@@H]1CC=C(C(O)=O)[C@](C)(C1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=SXHYCICJWKBOTK-VTFLLYPTNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138223   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))
BDBM50138223
PNG
(CHEMBL3753526)
Show SMILES C[C@@H]1CC=C(C(O)=O)[C@](C)(C1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C15H16Cl2O2/c1-9-3-5-11(14(18)19)15(2,8-9)10-4-6-12(16)13(17)7-10/h4-7,9H,3,8H2,1-2H3,(H,18,19)/t9-,15-/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.78E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Displacement of [125I]MCP-1 from CCR2 in human PBMC by radioligand displacement assay


Bioorg Med Chem Lett 26: 662-6 (2016)


Article DOI: 10.1016/j.bmcl.2015.11.051
BindingDB Entry DOI: 10.7270/Q2X068VS
More data for this
Ligand-Target Pair