BDBM50138691 5-(3,4-Dimethoxy-benzyl)-pyrimidine-2,4-diamine::CHEMBL19633::Diaveridine

SMILES: COc1ccc(cc1OC)Cc2cnc(nc2N)N

InChI Key: InChIKey=LDBTVAXGKYIFHO-UHFFFAOYSA-N

Data: 17 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50138691   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		11.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Salmonella typhi)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Escherichia coli)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		19.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Lactobacillus casei)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Lactobacillus casei)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Bovine)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bovine)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Bovine)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bifunctional dihydrofolate reductase-thymidylate synthase (Plasmodium Falciparum)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydrofolate reductase (Chicken)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Dihydrofolate reductase (Chicken)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Chicken)	BDBM50138691 (Diaveridine | 5-(3,4-Dimethoxy-benzyl)-pyrimidine-...) Show SMILES Show InChI	GoogleScholar	UniChem		3.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.2	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair