BDBM50139013 (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide::1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylicacid[1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-phenyl-ethyl]-amide::CHEMBL333357::H-Tyr-Pro-Phe-Phe-NH2::Tyr-Pro-Phe-Phe-NH2::endomorphin-2
SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key InChIKey=XIJHWXXXIMEHKW-LJWNLINESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 125 hits for monomerid = 50139013
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.00950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain homogenates by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Binding affinity against rat brain Opioid receptor mu 1 using [3H]-DAMGO radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]endomorphin-2 from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.33nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.35nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Clinical Research Institute Of Montreal
Curated by PDSP Ki Database
Clinical Research Institute Of Montreal
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 2.06nMAssay Description:Binding affinity towards mu receptor in rat brain using [3H]DAMGOMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DAMGO from rat cortex mu opioid receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]DAMGO from human recombinant MOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition of [3H]-naloxone binding to rat brain homogenate Opioid receptor muMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Displacement of [3H]-endomorphin-2 from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 8.23nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 8.23nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membraneMore data for this Ligand-Target Pair
Affinity DataKi: 8.70nMAssay Description:Displacement of [3H]SP1-7 from NK1 receptor in Sprague-Dawley rat spinal cord membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Inhibition of DAMGO (Tyr-[D-Ala]-Gly-[NMe-Phe]-Gly-ol) binding to rat brain mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.53nMAssay Description:Displacement of [3H]-DAMGO from Opioid receptor mu 1 of rat brain membranesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.56nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 9.60nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Biological Research Center Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 10.6nMAssay Description:Displacement of [3H]-Dynorphin A from Opioid receptor kappa 1 of rat brain membranes (DAMGO/DADLE quenching of mu/delta receptor binding)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-DAMGO from Wistar rat mu opioid receptor incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Affinity DataKi: >500nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
TargetOpioid receptor delta 1(Bos taurus)
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Affinity DataKi: >500nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in calf frontal cortex after 1 hr by gamma counterMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Affinity DataKi: 1.14E+3nMAssay Description:Displacement of [3H]U-69593 from human recombinant KOR expressed in CHO cell membranes incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.30E+3nMAssay Description:Inhibition of [3H]-naloxone binding to rat brain homogenate Opioid receptor deltaMore data for this Ligand-Target Pair
Affinity DataKi: 2.65E+3nMAssay Description:Displacement of [3H]Ile5,6-deltorphin II from opioid receptor delta 1 of rat brain membranesMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataKi: 2.71E+3nMAssay Description:Displacement of [3H]U69,593 from guinea pig cortex/cerebella kappa opioid receptor after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 3.39E+3nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor (unknown origin) expressed in CHO cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.94E+3nMAssay Description:Binding affinity towards delta receptor in rat brain using [3H]DSLETMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(MOUSE)
Clinical Research Institute Of Montreal
Curated by PDSP Ki Database
Clinical Research Institute Of Montreal
Curated by PDSP Ki Database
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataKi: >4.00E+3nMAssay Description:Displacement of [3H]U69,593 from kappa opioid receptor in Hartley guinea pig cerebellum P2 synaptosome membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Universit£ di Chieti-Pescara G. d'Annunzio
Curated by ChEMBL
Affinity DataKi: 5.24E+3nMAssay Description:Binding affinity to KOP (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5.65E+3nMAssay Description:Displacement of [3H]Ile5,6deltorphin-2 from delta opioid receptor in Wistar rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 6.08E+3nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in rat brain P2 synaptosomeMore data for this Ligand-Target Pair
Affinity DataKi: 6.09E+3nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
Affinity DataKi: 6.09E+3nMAssay Description:Binding affinity to delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.42E+3nMAssay Description:Displacement of [3H]DPDPE from Myc-tagged delta opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair