BDBM50139381 4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-benzonitrile::CHEMBL161825

SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1

InChI Key InChIKey=CKFMMVLRYYANSV-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139381   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139381(4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...)
Affinity DataKi:  8.70nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139381(4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...)
Affinity DataKi:  8.80nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139381(4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...)
Affinity DataKi:  59nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139381(4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...)
Affinity DataKi:  59nMAssay Description:Binding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed