BDBM50139393 4-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile::CHEMBL158740

SMILES CC1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C#N)CC1

InChI Key InChIKey=HRPKXNNRDDPCBN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50139393   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139393(4-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-benzofura...)
Affinity DataKi:  15nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139393(4-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-benzofura...)
Affinity DataKi:  15nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139393(4-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-benzofura...)
Affinity DataKi:  16nMAssay Description:Binding potency by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50139393(4-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-benzofura...)
Affinity DataKi:  16nMAssay Description:Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from histamine H3 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed