BDBM50139649 CHEMBL3764617
SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1\C=N\c1ccccc1NS(=O)(=O)c1ccc(C)cc1
InChI Key InChIKey=FLDBNMYJUMAXDQ-TURZUDJPSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50139649
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of recombinant human His6/HA-fusion-tagged SphK2 expressed in baculovirus infected sf9 insect cells using d-erythro-sphingosine as substra...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of recombinant human SphK2 assessed as decrease in [33P]SIP production using sphingosine as substrate in presence of [gamma33P]-ATP by sci...More data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Inhibition of human SK2 using D-erythro sphingosine as substrate and gamma[33P]ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6.90E+3nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Antagonistic activity against (-)-noradrenaline-induced contraction of rat thoracic aorta (Alpha-1D adrenergic receptor)More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of recombinant human SphK1 expressed in baculovirus infected Sf9 cells assessed as decrease in [33P]SIP production using D-erythro-sphingo...More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of human SK1 using D-erythro sphingosine as substrate and gamma[33P]ATP by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of recombinant human C-terminal TEV cleavage site-fused-His6-tagged SphK1 expressed in baculovirus infected sf9 insect cells using d-eryth...More data for this Ligand-Target Pair