BDBM50140506 (E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4-yl]-acrylamide::(E)-N-(1-acetylindolin-6-yl)-3-(3-cyanophenyl)-N-(1-(2-cyclopentylethyl)piperidin-4-yl)acrylamide::CHEMBL21283

SMILES CC(=O)N1CCc2ccc(cc12)N(C1CCN(CCC2CCCC2)CC1)C(=O)\C=C\c1cccc(c1)C#N

InChI Key InChIKey=DSEJCLDJIFTPPH-FMIVXFBMSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50140506   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50140506((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)
Affinity DataIC50:  100nMAssay Description:Binding affinity towards human NPY Y2 receptor was determined using [35S]-GTP-gammaS, radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50140506((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to neuropeptide Y2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50140506((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)
Affinity DataIC50:  63.1nMAssay Description:Antagonist activity at human neuropeptide Y2 receptor by [35]GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50140506((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]-NPY from NPYY2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50140506((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at NPYY2 receptor (unknown origin) assessed as inhibition of PYY-induced [33S]-GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50140506((E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cy...)
Affinity DataIC50:  100nMAssay Description:Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed