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BDBM50140573 CHEMBL3752343

SMILES: OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=VVWVTVVCTPSFQC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140573   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific demethylase 6B


(Homo sapiens (Human))
BDBM50140573
PNG
(CHEMBL3752343)
Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C20H20Cl2N6O2S/c21-14-2-1-13(11-15(14)22)27-6-8-28(9-7-27)17-12-16(19-23-5-10-31-19)25-20(26-17)24-4-3-18(29)30/h1-2,5,10-12H,3-4,6-9H2,(H,29,30)(H,24,25,26)
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Similars

Article
PubMed
n/an/a 940n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay


Bioorg Med Chem Lett 26: 721-5 (2016)


Article DOI: 10.1016/j.bmcl.2016.01.006
BindingDB Entry DOI: 10.7270/Q2P55QC2
More data for this
Ligand-Target Pair