BDBM50140795 1-(2-Bromo-phenyl)-3-(3-chloro-4-cyano-2-hydroxy-phenyl)-urea::CHEMBL27446

SMILES Oc1c(Cl)c(ccc1NC(=O)Nc1ccccc1Br)C#N

InChI Key InChIKey=DBRVLDHXULWYPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140795   

TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140795(1-(2-Bromo-phenyl)-3-(3-chloro-4-cyano-2-hydroxy-p...)
Affinity DataIC50: 22nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 2 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50140795(1-(2-Bromo-phenyl)-3-(3-chloro-4-cyano-2-hydroxy-p...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of binding of IL-8 to membranes of cloned CXC chemokine receptor 1 expressed in CHO Cells using [125I]IL-8 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed