BDBM50141075 6-[8-(2-Dimethylamino-ethoxy)-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl]-pyridin-2-ylamine::CHEMBL39005

SMILES CN(C)CCOc1ccc(c2C3CCC(C3)c12)-c1cccc(N)n1

InChI Key InChIKey=TXHKKANZSDSWIS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50141075   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141075(6-[8-(2-Dimethylamino-ethoxy)-1,2,3,4-tetrahydro-1...)
Affinity DataIC50:  1.08E+3nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141075(6-[8-(2-Dimethylamino-ethoxy)-1,2,3,4-tetrahydro-1...)
Affinity DataIC50:  185nMAssay Description:In vitro inhibition of rat neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141075(6-[8-(2-Dimethylamino-ethoxy)-1,2,3,4-tetrahydro-1...)
Affinity DataIC50:  1.90E+4nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50141075(6-[8-(2-Dimethylamino-ethoxy)-1,2,3,4-tetrahydro-1...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed