BDBM50141146 But-2-ynoic acid [5-(3-chloro-4-fluoro-phenylamino)-6-cyano-[1,8]naphthyridin-3-yl]-amide::CHEMBL287022

SMILES CC#CC(=O)Nc1cnc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1

InChI Key InChIKey=PWVHLRJTWXCLHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141146   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141146(But-2-ynoic acid [5-(3-chloro-4-fluoro-phenylamino...)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50141146(But-2-ynoic acid [5-(3-chloro-4-fluoro-phenylamino...)
Affinity DataIC50:  3.76E+3nMAssay Description:Inhibition of peptide substrate phosphorylation by epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed