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BDBM50141479 (E)-1-(3,5-Di-tert-butyl-4-methoxy-phenyl)-3-phenyl-propenone::CHEMBL38119

SMILES: COc1c(cc(cc1C(C)(C)C)C(=O)\C=C\c1ccccc1)C(C)(C)C

InChI Key: InChIKey=YJEOQYXOARWCLD-BUHFOSPRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141479   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tumor necrosis factor receptor R1


(Homo sapiens (Human))
BDBM50141479
PNG
((E)-1-(3,5-Di-tert-butyl-4-methoxy-phenyl)-3-pheny...)
Show SMILES COc1c(cc(cc1C(C)(C)C)C(=O)\C=C\c1ccccc1)C(C)(C)C
Show InChI InChI=1S/C24H30O2/c1-23(2,3)19-15-18(16-20(22(19)26-7)24(4,5)6)21(25)14-13-17-11-9-8-10-12-17/h8-16H,1-7H3/b14-13+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



AtheroGenics, Inc.

Curated by ChEMBL


Assay Description
Inhibition of TNF-alpha-induced VCAM-1 expression


Bioorg Med Chem Lett 14: 1513-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.021
BindingDB Entry DOI: 10.7270/Q2028QZK
More data for this
Ligand-Target Pair