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BDBM50141685 (S)-2-((S)-3-Amino-4-benzylsulfanyl-2-hydroxy-butyrylamino)-propionic acid ethyl ester::CHEMBL169482

SMILES: CCOC(=O)[C@H](C)NC(=O)C(O)[C@H](N)CSCc1ccccc1

InChI Key: InChIKey=WAUFRWRDADWDFP-MKDGSZCOSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM50141685
PNG
((S)-2-((S)-3-Amino-4-benzylsulfanyl-2-hydroxy-buty...)
Show SMILES CCOC(=O)[C@H](C)NC(=O)C(O)[C@H](N)CSCc1ccccc1
Show InChI InChI=1S/C16H24N2O4S/c1-3-22-16(21)11(2)18-15(20)14(19)13(17)10-23-9-12-7-5-4-6-8-12/h4-8,11,13-14,19H,3,9-10,17H2,1-2H3,(H,18,20)/t11-,13+,14?/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.10E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against human methionine aminopeptidase-2


Bioorg Med Chem Lett 14: 865-8 (2004)


Article DOI: 10.1016/j.bmcl.2003.12.031
BindingDB Entry DOI: 10.7270/Q2Z31Z3N
More data for this
Ligand-Target Pair