BDBM50142006 (R)-2-[(2S,3S)-3-{4-[5-(4-Chloro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid::CHEMBL369822

SMILES CCn1nc(Cc2ccc(Cl)cc2)cc1C1CCN(C[C@H]2CN(C[C@@H]2c2cccc(F)c2)[C@H](C(C)C)C(O)=O)CC1

InChI Key InChIKey=MXJBFVIZLFDIAO-NNYJQHGCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142006   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50142006((R)-2-[(2S,3S)-3-{4-[5-(4-Chloro-benzyl)-2-ethyl-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration for displacement of [125I]-MIP-1 alpha from recombinant human CC chemokine receptor 5 (CCR5) expressed in CHO cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed