BDBM50142007 (R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methanesulfonyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid::CHEMBL367461

SMILES CCn1nc(Cc2ccc(cc2)S(C)(=O)=O)cc1C1CCN(C[C@H]2CN(C[C@@H]2c2cccc(F)c2)[C@@H](C(O)=O)C(C)(C)C)CC1

InChI Key InChIKey=BRCFAGPWPWYSAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142007   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50142007((R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methanesulfonyl-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration to displace [125I]-MIP-1 alpha from human CX3C chemokine receptor 5 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed