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BDBM50142186 CHEMBL3760091

SMILES: Cc1ccc(cc1)-c1ncc(NCC2CCCNC2)cc1-c1ccc(cc1)C#N

InChI Key: InChIKey=IWDLSIOISOWIID-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142186   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))
BDBM50142186
PNG
(CHEMBL3760091)
Show SMILES Cc1ccc(cc1)-c1ncc(NCC2CCCNC2)cc1-c1ccc(cc1)C#N
Show InChI InChI=1/C25H26N4/c1-18-4-8-22(9-5-18)25-24(21-10-6-19(14-26)7-11-21)13-23(17-29-25)28-16-20-3-2-12-27-15-20/h4-11,13,17,20,27-28H,2-3,12,15-16H2,1H3
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Similars

Article
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Baylor College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...


J Med Chem 59: 253-63 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01361
BindingDB Entry DOI: 10.7270/Q23J3FSW
More data for this
Ligand-Target Pair