BDBM50142256 4-(4-tert-Butyl-benzenesulfonyl)-1-(3H-imidazol-4-ylmethyl)-2-phenethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine::CHEMBL8332

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1CC(CCc2ccccc2)N(Cc2cnc[nH]2)c2ccccc2C1

InChI Key InChIKey=YQGNXQWPWJAAKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50142256   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142256(4-(4-tert-Butyl-benzenesulfonyl)-1-(3H-imidazol-4-...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity of the compound against ccytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP synthase subunit beta,/delta,/epsilon,/gamma, mitochondrial(Bos taurus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142256(4-(4-tert-Butyl-benzenesulfonyl)-1-(3H-imidazol-4-...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against bovine mitochondrial F1F0-ATP synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP synthase subunit beta,/delta,/epsilon,/gamma, mitochondrial(Bos taurus)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50142256(4-(4-tert-Butyl-benzenesulfonyl)-1-(3H-imidazol-4-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory activity against bovine mitochondrial F1F0-ATP synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed